CLEVELAND (AP) — Marcus Mariota threw three touchdown passes — one a stunning 75-yarder to big back Derrick Henry — and the Titans rolled to a 43-13 win over the Browns, who fell flat on their faces in their highly anticipated opener.
The Browns committed 18 penalties, their most since 1951 and fell to 1-19-1 in openers since 1999.
Titans tight end Delanie Walker had two TD catches in the fourth quarter, and Tennessee intercepted Baker Mayfield three times in the fourth to pull away.
Mayfield had his right wrist wrapped after game.
He appeared to get hurt when he was sacked for a safety in the first half. Following the game, the Browns said X-rays taken on Mayfield were negative.