Royce Lewis had a grand slam and a career-high six RBIs, and Jorge Polanco and Carlos Correa added solo homers off Lucas Giolito in his Cleveland debut as the AL Central-leading Minnesota Twins beat the Guardians 20-6.
Spencer Steer hit a three-run home run to help the Reds beat the Seattle Mariners 6-3 in an interleague matchup of playoff contenders.
Taylor Walls drove in the go-ahead run with a single in the eighth inning as the Tampa Bay Rays salvaged the series finale with a 6-2 win over the Guardians, who missed a chance to gain ground on Minnesota in the AL Central.
The Clippers exploded for eight runs in the 10th inning and won a back-and-forth affair 14-6 at CHS Field Sunday to earn a split of a six-game series.
Ian Happ drove in four runs, Mike Tauchman and Cody Bellinger each drove in three and the Chicago Cubs beat the Reds 15-7.
Miyan Williams rushed for two touchdowns and No. 3 Ohio State beat Indiana 23-3 for its 23rd consecutive season-opening victory.
Cucho Hernández scored twice in the first half and finished off a hat trick with a penalty-kick goal in the second to spark the Columbus Crew to a 4-2 victory over CF Montreal on Saturday night.
Elly De La Cruz hit a tying single and newcomer Hunter Renfroe beat out a double-play ball to drive in the winner as the Reds rallied for two runs in the bottom of the ninth inning for the second straight night, defeating the Chicago Cubs 2-1.
Steven Kwan’s sacrifice fly brought home Bo Naylor after Jose Tena tied the score with a single in the 11th inning to lift the Guardians to a 7-6 victory over the Tampa Bay Rays.
Zack Collins ans George Valera hit solo home runs to lead the Clippers to a 4-1 win over the St. Paul Saints at CHS Field Saturday night.